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Volume 54, Number 1, February 2008

MINIREVIEW

Pharmacological Interventions to Prevent Vascular Endothelial Dysfunction: Future Directions
[Abstract], [Full-Text PDF (232 kB)]
Pitchai Balakumar, Rajeshkumar U. Koladiya, Subbiah Ramasamy, Andiappan Rathinavel, and Manjeet Singh.....1

REGULAR ARTICLES

Chlorination Byproducts of Epoxy Resin Hardener and Mutagenic Assay of Their Products
[Abstract], [Full-Text PDF (144 kB)]
Satoshi Tomiyama, Yasuo Takahashi, Kumiko Yaguchi, and Sukeo Onodera.....17

Present State of New Chiral Drug Development and Review in Japan
[Abstract], [Full-Text PDF (696 kB)]
Rumiko Shimazawa, Naomi Nagai, Satoshi Toyoshima, and Haruhiro Okuda.....23

Headache, Mental Health, and Use of Medical Resources: Health Diary Study in Japan
[Abstract], [Full-Text PDF (100 kB)]
Shin Yamazaki, Shunichi Fukuhara, Joseph Green, Osamu Takahashi, Takuro Shimbo, Hiroyoshi Endo, Shigeaki Hinohara, and Tsuguya Fukui.....30

Vulnerability to Seizures Induced by Potassium Dyshomeostasis in the Hippocampus in Aged Rats
[Abstract], [Full-Text PDF (1.60 MB)]
Atsushi Takeda Naomi Sakurada Shingo Kanno Masaki Ando and Naoto Oku.....37

Essential Role of Ascorbic Acid in Neural Differentiation and Development: High Levels of Ascorbic Acid 2-Glucoside Effectively Enhance Nerve Growth Factor-Induced Neurite Formation and Elongation in PC12 Cells
[Abstract], [Full-Text PDF (684 kB)]
Mari Haramoto, Hideki Tatemoto, and Norio Muto.....43

Effect of Sargassum horneri Extract on Circulating Bone Metabolic Markers: Supplemental Intake Has an Effect in Healthy Humans
[Abstract], [Full-Text PDF (256 kB)]
Toru Matsumoto, Yoshinori Hokari, Masayuki Hashizume, and Masayoshi Yamaguchi.....50

Homocysteine Inhibits Proteoglycan Synthesis in Cultured Bovine Aortic Smooth Muscle Cells
[Abstract], [Full-Text PDF (576 kB)]
Yasuyuki Fujiwara, Chihiro Mikami, Michinori Nagai, Chika Yamamoto, Takashi Hirooka, Masahiko Satoh, and Toshiyuki Kaji.....56

RESEARCH LETTERS

Response of Human Lymphocytes In Vitro to Two Dietary Furans, Furfuryl Alcohol and 2-Furyl Methyl Ketone
[Abstract], [Full-Text PDF (96.0 kB)]
Pillai Sasidharan Sujatha.....66

Determination of D-Malate Using Immobilized D-Malate Dehydrogenase in a Flow System and its Application to Analyze the D-Malate Content of Beverages
[Abstract], [Full-Text PDF (112 kB)]
Hisakazu Mori and Satoshi Shiraki.....72

Preventive Effects of 80% Ethanol Extracts of the Edible Mushroom Hypsizigus marmoreus on Mouse Type IV Allergy
[Abstract], [Full-Text PDF (284 kB)]
Kyoji Yoshino, Youko Kondou, Kinuko Ishiyama, Tetsuro Ikekawa, Tsunetomo Matsuzawa, and Mitsuaki Sano.....76

Inhibitory and Killing Activities of Medicinal Plants against Multiple Antibiotic-resistant Helicobacter pylori
[Abstract], [Full-Text PDF (416 kB)]
Supayang Piyawan Voravuthikunchai and Hazel Mitchell.....81

Analysis of Phenethylamines and Tryptamines in Designer Drugs Using Gas Chromatographymass Spectrometry
[Abstract], [Full-Text PDF (1.79 MB)]
Misako Takahashi, Machiko Nagashima, Jin Suzuki, Takako Seto, Ichirou Yasuda, and Takemi Yoshida.....89

Gender-Related Differences in the Level of Serum Lipids in Meishan Pigs
[Abstract], [Full-Text PDF (128 kB)]
Misaki Kojima, Masashi Sekimoto, and Masakuni Degawa.....97

Evaluation of Genetic and Developmental Toxicity of Surfactin C from Bacillus subtilis BC1212
[Abstract], [Full-Text PDF (100 kB)]
Youn-Hwan Hwang, Byung-Kwon Park, Jong-Hwan Lim, Myoung-Seok Kim, In-Bae Song, Seung-Chun Park, and Hyo-In Yun.....101

Factor Analysis of Drug Supply Time Series at Pharmacies
[Abstract], [Full-Text PDF (200 kB)]
Tsuyoshi Kobari, Hisako Takeuchi, Kazuo Iwaki, Fumiyoshi Ishii, Hiroe Tsubaki, Rieko Matsuda, Yuzuru Hayashi, and Takehiko Yajima.....107

RAPID COMMUNICATIONS

Extract of Alpinia officinarum Suppresses Enteropathogenic Escherichia coli (EPEC) Lipopolysaccharide (LPS) Induced Inflammation in J774 A.1 Macrophages
[Abstract], [Full-Text PDF (476 kB)]
Krishnan Subramanian, Chinnasamy Selvakkumar, Sankaranarayanan Meenakshisundaram, Arun Balakrishnan, and Baddireddi Subhadra Lakshmi.....112

Evaluation of Endocrine Disrupting Activities of Monohydroxylated Derivatives of 1-nitropyrene by Yeast Two-hybrid Assay
[Abstract], [Full-Text PDF (224 kB)]
Takayuki Kameda, Ayuko Akiyama, Akira Toriba, Chihiro Tachikawa, Morio Yoshita, Ning Tang, and Kazuichi Hayakawa.....118

16S rRNA Sequence-based Rapid and Sensitive Detection of Aquatic Bacteria by On-chip Hybridization Following Multiplex PCR
[Abstract], [Full-Text PDF (200 kB)]
Tomoaki Ichijo, Nobuyasu Yamaguchi, Katsuji Tani, and Masao Nasu.....123