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J.Health Sci., 54(1), 97-100, 2008

Gender-Related Differences in the Level of Serum Lipids in Meishan Pigs

Misaki Kojima,*, a Masashi Sekimoto,b and Masakuni Degawab

aAnimal Genome Research Unit, Division of Animal Sciences, National Institute of Agrobiological Sciences, 2-1-2 Kannondai, Tsukuba 305-8602, Japan and bDepartment of Molecular Toxicology and Global COE Program, School of Pharmaceutical Sciences, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

Levels of serum lipids such as total cholesterol (TCHO), free cholesterol (F-CHO), low density lipoprotein cholesterol (LDL-C), triglycerides (TG), and phospholipids (PL) were examined in both sexes of Meishan pigs. In young adult pigs (4- to 5-monthold), levels of all above lipids mentioned were significantly higher in females than in males, while no such sex difference was observed until the age of 3 months. In young adult male pigs castrated at the age of 1 month, levels of these lipids were almost the same as levels in corresponding female pigs. In addition, no sex differences in the levels of high density lipoprotein cholesterol and non-esterified free fatty acids were observed. The present findings indicated that androgen might act as a down-regulator for the levels of serum lipids, such as T-CHO, F-CHO, LDLC, TG and PL, in pigs.