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Volume 57, Number 1, February 2011


The Role of Mitochondrial Chaperone Tumor Necrosis Factor-associated Protein 1 (TRAP1) in the Regulation of Apoptosis
[Abstract], [Full-Text PDF (416 kB)]
Yutaka Masuda.....1

Development and Application of Sensitive Methods with Luminescence Detections for Determination of Biologically Active Compounds
[Abstract], [Full-Text PDF (524 kB)]
Kenichiro Nakashima.....10

Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver
[Abstract], [Full-Text PDF (184 kB)]
Chie Emoto, Kazuhide Iwasaki, Norie Murayama, and Hiroshi Yamazaki.....22


Dichloroacetate Inhibits Vascular Remodeling and Increases Voltage-gate K+ Expression in a High-altitude-induced Pulmonary Artery Hypertension Rat Model
[Abstract], [Full-Text PDF (0.98 MB)]
Xian-hua Xu, Hua-sheng Peng, Mei-qin Sun, Meng Hu, Wan-hua Wang, Ru Zhang, and Xin-rong Xiao.....28

The Efficacy of Costus igneus Rhizome on Carbohydrate Metabolic, Hepatoproductive and Antioxidative Enzymes in Streptozotocin-induced Diabetic Rats
[Abstract], [Full-Text PDF (168 kB)]
Pazhanichamy Kalailingam, Aiswarya Devi Sekar, Jeba Samuel Clement Samuel, Priya Gandhirajan, Yogha Govindaraju, Manjula Kesavan, Rajendran Kaliaperumal, Kumaran shanmugam, and Eevera Tamilmani.....37

Determination of Liothyronine and Levothyroxine in Dietary Supplements by HPLC Using a Pre-column Derivative
[Abstract], [Full-Text PDF (412 kB)]
Yoshiyuki Sawabe, Takaomi Tagami, Katsuhiro Yamasaki, and Shuzo Taguchi.....47

Determination of 3,6-Dinitrobenzo[e]pyrene in Tea Leaves as a Possible Exposure Source and in Human Hair as a Biomarker Using a Two-dimensional HPLC System
[Abstract], [Full-Text PDF (296 kB)]
Tomohiro Hasei, Atsumi Ohno, Rie Tsukuda, Tatsuro Inoue, and Tetsushi Watanabe.....53

A Single Instillation of Amorphous Silica Nanoparticles Induced Inflammatory Responses and Tissue Damage until Day 28 after Exposure
[Abstract], [Full-Text PDF (392 kB)]
Eun-Jung Park, Jinkyu Roh, Younghun Kim, and Kyunghee Choi.....60

Preparation of Oligoselenodiglutathiones and Their Suppressive Effects on Oxidative DNA Damage Induced by Catechol and Copper
[Abstract], [Full-Text PDF (396 kB)]
Motozumi Ando, Hiroyuki Nishida, Koji Ueda, Kazuo Itoh, Yoshinori Okamoto, and Nakao Kojima.....72


Substrate Specificity of Mutanase of Paenibacillus humicus from Fermented Food
[Abstract], [Full-Text PDF (208 kB)]
Hideaki Tsumori, Atsunari Shimamura, Yutaka Sakurai, and Kazuo Yamakami.....78

Hypothermia after Reperfusion Suppresses Aggravation of Acute Brain Edema following Transient Forebrain Ischemia in Mice
[Abstract], [Full-Text PDF (168 kB)]
Masaru Doshi, Etsuka Higuchi, and Yutaka Hirashima.....82

Potent Inhibition of Platelet-Derived Growth Factor-Stimulated Rat Aortic Vascular Smooth Muscle Cell Cycle and Proliferation by (2E)-3-(4-hydroxy-3-methoxyphenyl)phenylpro-2-en-1-one, a Newly Synthesized Benzylideneacetophenone Derivative
[Abstract], [Full-Text PDF (324 kB)]
Tack-Joong Kim, Hyeong-Jun Han, Jae-Chul Jung, Seikwan Oh, and Yeo-Pyo Yun.....86


Differential Effects of Two Types of Obesity on Ketone Body Utilization in Skeletal Muscle
[Abstract], [Full-Text PDF (336 kB)]
Ryota Narishima, Masahiro Yamasaki, Saki Yoshida, Shinya Hasegawa, and Tetsuya Fukui.....93

Characterization of a 62-Kilodalton Acidic Phospholipid-Binding Protein Isolated from the Edible Mushroom Pleurotus ostreatus
[Abstract], [Full-Text PDF (256 kB)]
Hideko Tanaka and Tetsuyuki Kobayashi.....99

Two-Electron Quinone Reductase (Aldo-keto Reductase 1C Isozyme) Augments the Oxidative DNA Damage Induced by Quinones in Diesel Exhaust Particles by Accelerating Redox Cycling
[Abstract], [Full-Text PDF (284 kB)]
Shigeru Yamano, Mie Shibata, Hideki Kita, Kimihiko Matsusue, Shizuo Narimatsu, Keiko Taguchi, and Yoshito Kumagai.....107