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J.Health Sci., 53(1), 132-136, 2007
Measurement of Carbon Monoxide in Exhaled Breath as a Possible Marker of Stress
Hayami Nitta,a Maki Kinoyama,a
Akiharu Watanabe,*, a Yoshiaki Fujita,a
Hideo Ueda,b and Kunihisa Shiraoc
aDepartment of Clinical Nutrition, Faculty of Health Science and Technology, Kawasaki University of Medical Welfare, 288 Matsushima, Kurashiki, Okayama 701-0193, Japan,
bMitleben R & D Associate, 1-23-1205 Kitamidorigaoka, Toyonaka, Osaka 560-0001, Japan, and
cAcqua Plus Co., Ltd., 14-6 Sakuragaoka, Shibuya, Tokyo 150-0031, Japan
We measured the concentration of carbon monoxide (CO) gas in exhaled breath and the level of stress in students to evaluate their lifestyle and mental health for the annual medical checkup at our University. 993 students were examined for CO by gas analysis device and 445 selected randomly from them for stress levels by a Stressometer. CO concentration in breath is markedly higher in the case of smokers and slightly higher in non-smokers who are exposed to passive smoking. Students with a tremor of the nervous system at rest (TNR) higher than 70 in a Stressometer were found in 13.0%, and in nonsmoking female students there was a significant correlation between stress levels and CO concentration in the breath which is produced in the cells by stressinduced heme oxygenase-1. The results of the present study suggest that measuring CO gas may be a convenient way to evaluate lifestyle and stress levels in students.
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