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J.Health Sci., 52(6), 817-820, 2006

Effects of Drinking a Water Product with Anti-Oxidant Activities In Vitro on the Blood Levels of Biomarker Substances for the Oxidative Stress

Atsushi Hiraoka,*, a Satoshi Sasaki,a Tomoko Yamada,a Atsuko Shinohara,b and Momoko Chibab, 1

aDepartment of Pathological Biochemistry, Faculty of Health Sciences, Kyorin University, Hachioji-shi, Tokyo 192-8508, Japan and bDepartment of Epidemiology and Environmental Health, Juntendo University School of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan

The in vivo effects of drinking a water product, which had been confirmed to have antioxidant activities in vitro, were preliminarily studied by monitoring the blood concentrations of oxidative stress marker substances in the two group subjects who ingested the same quantity of the water product and a tap water solution during the same time. The results indicated that hydrogen gas and reductive vanadium ions as the components responsible for the antioxidant activities in vitro cannot enhance the scavenging ability for reactive oxygen species in vivo after being drunk and absorbed into the human body, although it was suggested that an ingestion of a greater quantity of water than usual gives a slight reduction, overall, in the oxidative stress.