| |
Software Requirements
Microsoft Internet Explorer 5.01 or higher and Netscape Navigator 4.75 or higher are recommended. |
|
 |
J.Health Sci., 51(6), 708-710, 2005
Antidiabetic Activity of Green Tea (Thea sinensis L.) in Genetically Type 2 Diabetic Mice
Toshihiro Miura,*, a Tomoko Koike,a and Torao Ishidab
aDepartment of Clinical Nutrition, and bHi-tech Research Center, Suzuka University of Medical Science, 1001-1 Kishioka, Suzuka, Mie 510-0293, Japan
The antidiabetic activity of Thea sinensis was investigated in KK-Ay mice, an animal model of genetically type 2 diabetes with hyperinsulinemia. The water extract of Thea sinensis (green tea cold ext) (100 mg/kg body weight) reduced the blood glucose of KK-Ay mice 4 and 8 weeks after repeated administration and tended to decrease the plasma insulin level of KK-Ay mice under similar conditions. However, green tea cold ext did not affect blood glucose levels in normal mice. Green tea cold ext decreased blood glucose levels in an insulin tolerance test. These results suggest that the antidiabetic activity of green tea cold ext is derived, at least in part, from a decrease in plasma insulin, due to decreased insulin resistance.
|
|
