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J.Health Sci., 50(6), 666-669, 2004
The Association of Blood Biochemical Parameters
with Myocardial Infarction
Mohamad Khalid Nusier,*, a Zeyad
El-Akawi,a and Sameer Abd-Alkareem Otoomb
aDepartment of Biochemistry and Molecular Biology and
bDepartment of Pharmacology, Faculty of Medicine, Jordan
University of Science and Technology, P.O. Box 3030, Irbid
22110, Jordan
Biochemical changes that occurred in the blood
of myocardial infarction patients were investigated.
Two hundred and fifty two patient, 180 males and 72 females were involved in this study. The mean age
was 49.3 ± 9.25 years. Biochemical parameters
including serum total protein, albumin, total bilirubin, and
total cholesterol to albumin ratio were analyzed.
Biochemical parameters showed that the increased level
of triglyceride and total bilirubin were associated with
myocardial infarction. Triglyceride and total
bilirubin levels in myocardial infarction patients were 2.3 ±
1.4 mmol/l and 12.3 ± 3.2 mu mol/l respectively, whereas
those of healthy controls were 1.7 ± 1.2 mmol/l for
triglyceride and 9.7 ± 3.7 mu mol/l for bilirubin. On the other
hand, serum total protein and albumin concentrations
were lower in myocardial infarction patients compared
with those of controls. Total protein level was 65.5 ±
3.1 g/l in myocardial infarction patients and 76.2 ±
5.3 g/l in healthy controls. Albumin levels in both
patients and controls were 40.2 ± 3.2 g/l and 45.4 ±
4.5 g/l correspondingly. Interestingly, serum total cholesterol
level was not significantly different in myocardial
infarction patients compared with controls. Patients
cholesterol level was 5.8 ± 1.3 mmol/l and that of controls
was 5.2 ± 1.2 mmol/l. In addition, cholesterol/albumin
ratio in infarction patients (0.14 ± 0.04) found to be
significantly higher than that in healthy controls (0.11
± 0.03).
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