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J.Health Sci., 49(4), 249-259, 2003

-Review-

Using Simulation Models to Assess the Ecological Risk of Pesticides to Aquatic Organisms

Manabu Tsuzuki,*, a Ayumu Inoue,a Yoshiyuki Takimoto,a and Tsutomu Nishiharab

aEnvironmental Health Science Laboratory, Sumitomo Chemical Co., Ltd., 4-2-1 Takatsukasa, Takarazuka, Hyogo 665-8555, Japan and bGraduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan

The ecologic risk assessments consisting of hazard and exposure analysis are of prime importance for pesticide registration. In particular, the U.S.A.'s assessment on aquatic environment using simulation model is well organized. We introduce the current methods and ECOFRAM (Ecological Committee on FIFRA Risk Assessment Methods) by describing the case of pyrethroid insecticide as an example.