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J.Health Sci., 49(2), 129-137, 2003
Profiling of Illegal Amphetamine-type Stimulant
Tablets in Japan
Yukiko Makino,*, a Satoshi
Tanaka,a Shingo
Kurobane,a Masato
Nakauchi,a Takahiro
Terasaki,a and Shigeru
Ohtab
aNarcotics Control Department, Kanto-Shin'etsu Regional Bureau of Health and Welfare, Ministry of Health, Labour and
Welfare, 2-4-14 Nakameguro, Meguro-ku, Tokyo 153-0061, Japan and
bGraduate School of Biosciences, Hiroshima University,
1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan
We have investigated 100 illegal amphetamine-type stimulant (ATS) tablets seized in Japan to obtain
information about the nature of these tablets abused in Japan. For physical characterization, 15 items (logo, vertical
view, colour, diameter, weight, smell, etc.) were measured and a photograph was taken. For chemical
characterization, the components in the tablet were identified by GC-MS and HPLC, and quantified by HPLC using an
ODS-type column. The maximum content of N-methyl-3,4-methylenedioxyamphetamine (MDMA) was 189
mg/tablet and that of 3,4-methylenedioxyamphetamine (MDA) was 87 mg/tablet. The detected components,
other than MDMA and MDA, were N-ethyl-3,4-methylenedioxyamphetamine (MDEA), ephedrine, caffeine,
ketamine, and methamphetamine. In this report, we propose a method for profiling ATS tablets.
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