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J.Health Sci., 48(1), 93-95, 2002
Effect of Bisphenol A on the Feeding Behavior of Caenorhabditis elegans
Shinya Kohra,*, a Kazuko Kuwahara,a Yuji Takao,a Yasuhiro Ishibashi,b Ho Chul Lee,c Koji Arizono,d and Nobuaki Tominagae
aFaculty of Environmental Sciences, bEnvironmental Protection Center, and cGraduate School of Science and Technology, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan, dFaculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, 3-1-100 Tsukide, Kumamoto 862-8502, Japan, and eDepartment of Chemical and Biological Engineering, Ariake National College of Technology, 150 Higashihagino-machi, Omuta 836-8585, Japan
We observed and evaluated the feeding behavior of the free-living nematode Caenorhabditis elegans (C. elegans) after exposure to bisphenol A (BPA) and nonylphenol (NP). Exposed organisms were transferred to chemical-free culture medium and their attainment levels (the number of worms reaching the food source divided by the total number of worms on the Petri plate) were recorded after 2, 4, 6, 8, and 24 hr. Results showed a significant decrease in the attainment level of worms exposed to 10 mu M and 0.1 mu M BPA. However, there was a slight increase in the attainment level of nematodes treated with 1 mu M NP. These results differ from previous studies showing NP as being more lethal to nematodes than BPA.
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